02835nas a2200193   4500008004100000020001400041024001700055245008100072210006900153260034900222300001600571490000800587520192300595100001702518700002002535700002202555700001902577856004502596       2001                        eng d  a0028-4793  a0255562, now00aTransfusion-Transmitted Malaria in the United States from 1963 through 1999.0 aTransfusionTransmitted Malaria in the United States from 1963 th  aOwned, published, and (C) copyrighted, 2001, by the MASSACHUSETTS MEDICAL SOCIETYbFrom the Divisions of Parasitic Diseases (M.M., M.P.) and Viral and Rickettsial Diseases (M.C.), National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta; the Public Health Service, Department of Health and Human Servicc2001  a1973 - 19780 v3443 aBackground: Transfusion-transmitted malaria is uncommon in the United States. After the report of three cases of complicated Plasmodium falciparum infection acquired by transfusion, we reviewed all cases of transfusion-transmitted malaria reported to the Centers for Disease Control and Prevention (CDC) from 1963 through 1999., Methods: Information on the patients was from surveillance reports sent to the CDC. Information about the implicated blood donors came from the National Malaria Surveillance System. To determine whether donors should have been excluded from donating blood, we compared their characteristics with the exclusion guidelines of the Food and Drug Administration and the American Association of Blood Banks., Results: Of 93 cases of transfusion-transmitted malaria reported in 28 states, 33 (35 percent) were due to P. falciparum, 25 (27 percent) were due to P. vivax, 25 (27 percent) were due to P. malariae, 5 (5 percent) were due to P. ovale, 3 (3 percent) were mixed infections, and 2 (2 percent) were due to unidentified species. Ten of the 93 patients (11 percent) died. There were potentially 91 donors (in two cases, two patients received blood from the same donor), 67 of whom (74 percent) could be identified as infective. Of 64 implicated donors whose country of origin was reported, 38 (59 percent) were foreign born. Among those for whom complete information was available, 37 of 60 donors (62 percent) would have been excluded from donating according to current guidelines (in place since 1994), and 30 of 48 donors (62 percent) should have been excluded under the guidelines in place at the time of donation., Conclusions: Careful screening of donors according to the recommended exclusion guidelines remains the best way to prevent transfusion-transmitted malaria. (N Engl J Med 2001;344:1973-8.), Owned, published, and (C) copyrighted, 2001, by the MASSACHUSETTS MEDICAL SOCIETY1 aMungai, Mary1 aTegtmeier, Gary1 aChamberland, Mary1 aParise, Monica  uhttp://613633.bywedr.asia/reference/4002