| Title | Mobilization of peripheral blood progenitor cells for allogeneic transplantation |
| Publication Type | Journal Article |
| Year of Publication | 1997 |
| Authors | Teshima A, Harada M |
| Journal | Cytokines, Cellular & Molecular Therapy |
| Volume | 3 |
| Issue | 2 |
| Pagination | 101 - 14 |
| Keywords | *Granulocyte Colony-Stimulating Factor / ad [Administration & Dosage], *Hematopoietic Stem Cell Transplantation / mt [Methods], *Hematopoietic Stem Cells / cy [Cytology], *Hematopoietic Stem Cells / de [Drug Effects], Antigens, CD34 / me [Metabolism], Blood Donors, Cell Count, Cytokines / ad [Administration & Dosage], Cytokines / ae [Adverse Effects], Ethics, Medical, Graft Survival, Granulocyte Colony-Stimulating Factor / ae [Adverse Effects], Hematopoietic Stem Cell Transplantation / td [Trends], Hematopoietic Stem Cells / im [Immunology], Humans, Kinetics, Leukapheresis / ae [Adverse Effects], Lymphocytes / cy [Cytology], Lymphocytes / de [Drug Effects], Monocytes / cy [Cytology], Monocytes / de [Drug Effects], Safety, Thrombocytopenia / et [Etiology], Transplantation, Homologous |
| Abstract | Allogeneic transplantation of peripheral blood stem/progenitor cells (PBSC/PBPC) has been increasingly used as an alternative to allogeneic bone marrow transplantation. To mobilize and collect a sufficient number of PBSC/PBPC for engraftment after allotransplantation, granulocyte colony-stimulating factor (G-CSF) has been preferentially used. The mobilization protocol, however, has not been fully established. In this review, dose and schedule of G-CSF administration, characteristics of G-CSF-mobilized PBPC products, cytokines other than G-CSF for PBSC/PBPC mobilization, and safety of the PBSC/PBPC donors are discussed for clinical application of allogeneic PBSC/PBPC transplantation. [References: 106] |
| Short Title | Mobilization of peripheral blood progenitor cells for allogeneic transplantation |
| Notify Library Reference ID | 1532 |
