| Title | Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis |
| Publication Type | Journal Article |
| Year of Publication | 1995 |
| Authors | Gupta P, Hurley RW, Helseth PH, Goodman JL, Hammerschmidt DE |
| Journal | American Journal of Hematology |
| Volume | 50 |
| Issue | 1 |
| Pagination | 60 - 62 |
| Date Published | Sep |
| ISSN | 0361-8609; 0361-8609 |
| Accession Number | PMID: 7668227 |
| Keywords | Babesiosis / complications, Histiocytosis, Non-Langerhans-Cell / complications / etiology, Humans, Kidney Transplantation, Male, Middle Aged, Pancytopenia / etiology, Splenectomy |
| Abstract | We present a case of hemophagocytosis during infection with the intraerythrocytic protozoan Babesia microti in a 47-year-old splenectomized renal allograft recipient. After therapy with clindamycin and quinine a relapse responded to atovaquone; durable remission was not achieved until trimethoprim/sulfa was added. We postulate the severity of our patient's syndrome was due to splenectomy and chronic immunosuppression. Babesiosis should be considered when immunocompromised patients develop pancytopenia. |
| Alternate Journal | Am.J.Hematol. |
| Notify Library Reference ID | 1709 |
