Prophylaxis and treatment of Chagas disease in renal transplant donor and recipient: case report.

TitleProphylaxis and treatment of Chagas disease in renal transplant donor and recipient: case report.
Publication TypeJournal Article
Year of Publication2010
AuthorsOrtiz AM, Troncoso P, Sainz M, Vilches S
JournalTransplantation proceedings//Transplant Proc
Volume42
Issue1
Pagination393 - 4
Date Published2010
ISBN Number1873-2623
Other Numberswe9, 0243532
Keywords*Chagas Disease/dt [Drug Therapy], *Chagas Disease/pc [Prevention & Control], *Kidney Failure, Chronic/su [Surgery], *Kidney Transplantation/im [Immunology], *Nitrofurazone/tu [Therapeutic Use], Adult, Anti-Infective Agents/tu [Therapeutic Use], Chagas Disease/co [Complications], Chagas Disease/tm [Transmission], Histocompatibility Testing, HLA-A Antigens/im [Immunology], HLA-B Antigens/im [Immunology], HLA-DR Antigens/im [Immunology], Humans, Kidney Failure, Chronic/co [Complications], Living Donors, Male, Middle Aged, Polymerase Chain Reaction
Abstract

Chagas disease is a prevalent zoonosis in Latin America, caused by the protozoa Trypanosoma cruzi and transmitted by Triatoma infestans. Part of the infectious cycle consists of chronic subclinical parasitemia, causing in the long term end-organ damage. Amastigotes have been isolated from various organs including native and allograft renal parenchyma; thus, transplantation plus immunosuppression therapy is another mode of disease transmission and reactivation. Herein, we report 2 successful kidney transplantations cases in which either infection or reactivation was averted using prophylactic nitroderivates.
Notify Library Reference ID4299

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